PhD position (f/m/x) CRC 1218 on „mitochondrial regulation of cellular function“

PhD position (f/m/x)

CRC 1218 on „mitochondrial regulation of cellular function“

We are one of the largest and oldest universities in Europe and one of the most important employers in our region. Our broad range of subjects, the dynamic development of our main research areas and our central location in Cologne make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration.

In the framework of the Collaborative Research Centre (CRC) 1218 on “Mitochondrial regulation of cellular function” (www.sfb1218.uni-koeln.de), scientists from different research institutions in Cologne have teamed up to study how mitochondria influence activity, differentiation and survival of the cell. The CRC1218 has been funded by the German Research Foundation (DFG) since July 2016. The Riemer lab (http://riemerlab.uni-koeln.de/) – part of the CRC1218 and located at the University of Cologne‘s Institute for Biochemistry – is looking for a doctoral student. Research in the Riemer laboratory focuses on different aspects of redox and mitochondrial biology. For example, we characterize the mechanisms of disulphide formation and hydrogen peroxide signalling in different cellular com¬partments. We are also interested in the physiological impacts of these processes for example in calcium and in metabolic signalling (Petrungaro et al, Cell Metabolism, 2015; Habich et al, Cell Reports, 2019; Calabrese et al, EMBO J, 2019 and Höhne et al, EMBO J, 2022).

YOUR TASKS

• The doctoral candidate will perform a wide variety of biochemical and cell biological experiments including unbiased omics experiments and approaches with genetically encoded fluorescent proteins to uncover molecular mechanisms underlying different aspects of redox signalling from and in mammalian mitochondria.

YOUR PROFILE

• We are looking for a doctoral candidate with a background in molecular biology, biochemistry, molecular medicine or biological chemistry.
• A Master‘s thesis on a topic related to the molecular mechanisms of cellular processes would be an advantage.
• Ability to plan experiments, develop methods, carry out analyses and summarize results in English is a requirement

WE OFFER

• The doctoral candidate can build on the complementary expertise present in the CRC1218, .the excellent, state-of-the-art core facilities and the thriving, highly interactive scientific community in Cologne
• The candidate will expand his*her scientific horizon through participation in an interactive tailor-made educational program, the mito-RTG, that covers broad principles, and specific scientific and career development needs
• A diverse working environment with equal opportunities
• Support in balancing work and family life
• Extensive advanced training opportunities
• Occupational health management offers
• Flexible working time models

The University of Cologne promotes equal opportunities and diversity. Women will be considered preferentially in accordance with the Equal Opportunities Act of North Rhine-Westphalia (Landesgleichstellungsgesetz – LGG NRW). We also expressly welcome applications from all suitable candidates regardless of their gender, nationality, ethnic and social origin, religion, disability, age, sexual orientation and identity.

The position is available from 1 January 2025 on a part-time basis (25,89 hours per week).The position is to be filled for a fixed term of up to 2 years. An extension of the contract is possible. If the applicant meets the relevant wage requirements and personal qualifications, the salary is based on remuneration group 13 TV-L of the pay scale for the German public sector.

Please apply online with proof of the required qualifications without a photo under: jan.riemer@uni-koeln.de The reference number is Wiss2409-08.

The application deadline is 31 October 2024.

For further inquiries, please contact Professor Dr Jan Riemer (jan.riemer@uni-koeln.de).